CAS No.: | 103-63-9 |
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Formula: | C8h9br |
EINECS: | 203-130-8 |
Type: | Pharmaceutical Intermediates |
Appearance: | Liquid |
Quality: | Industrial |
Samples: |
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Customization: |
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2-Phenylethylbromide is an organobromide that can be produced by the action of and red phosphorus on 2-phenylethanol.
It is moderately toxic by ingestion.
When reacted with hydrazine, phenelzine is produced.
β-bromo-phenylethane is an important intermediate in the synthesis of highly effective bromo-based flame retardants polybromo-styrene, and is also commonly used in the preparation of organic synthesis intermediates. For example, β-bromophenethane can be used to prepare the intermediate 4-(4-phenylbutoxy) benzoic acid of Prelenast. As an anti-asthma drug, Prelunast was first developed by Ono Company in Japan, and was listed in Japan in 1995, and in 1999 Chemicalbook, it was found to treat allergic rhinitis. Prelenast is a leukotriene C4/D4 receptor antagonist (lTRAs) with extremely low toxicity. It can selectively inhibit the activity of leukotriene multiskin in airway smooth muscle, and has almost no effect on arachidonic acid metabolic enzymes. At the same time, it has no antagonistic effect on acetylcholine and 5-hydroxytryptamine, and significantly inhibits lTC4, lTD4 and lTE4.
Melting point | -56 °C |
Boiling point | 220-221 °C(lit.) |
density | 1.355 g/mL at 25 °C(lit.) |
refractive index | n20/D 1.556(lit.) |
Fp | 193 °F |
storage temp. | 2-8°C |
solubility | 0.039g/l |
form | Liquid |
color | Clear colorless to pale yellow |
β-bromo-phenylethane is an important intermediate in the synthesis of highly effective bromo-based flame retardants polybromo-styrene, and is also commonly used in the preparation of organic synthesis intermediates. Preparation of 2-nitro-3-phenyl-1-chemicalbook propyl alcohol. 2 -nitro-3- phenyl -1-propyl alcohol is a kind of important pharmaceutical intermediates in the preparation of all synthetic antimicrobial agent (R) 4- benzyl- 2-oxazole alkane ketone in plays an important role.
Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. Main products are cas: 6080-56-4, 2-phenylacetamide (cas103-81-1), After many years of efforts, we have established stable and friendly business relations with dozens of European and American pharmaceutical companies, multinational chemical companies and importers.
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