CAS No.: | 73536-69-3 |
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Formula: | C20h18o10 |
EINECS: | 1806241-263-5 |
Type: | Synthesis Material Intermediates |
Appearance: | Powder |
Quality: | Industrial |
Samples: |
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Customization: |
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Bifendate isan intermediate in the synthesis of Schisandrin C and can also be used as an anti-HBV drug to treat chronic hepatitis B.
Bifendate is a synthetic intermediate of Schisandrin C and also an anti-HBV drug used in Chinese medicine for the treatment of chronic hepatitis B. Following the intake of Bifendate in rats, the drug was observed to improve liver function by increasing the detoxification process, reducing pathological lesions, and accelerating hepatocyte regeneration. Bifendate can also function as a membrane-stabilizing agent to protect the cell from damage. After treatment with Bifendate, the protein metabolic processes of hepatitis patients were improved, with increased serum albumin levels and decreased globulin levels. Bifendate is a potent inducer of cytochrome proteins (CYPs) and can result in clinically significant interactions. It has been proposed that the increased detoxification capability of Bifendate originates from an increase in the level of P450. Bifendate may function as a protecting agent to prevent drug-induced liver dysfunction by increasing the activity.
Product Name | Bifendate |
CAS NO. | 73536-69-3 |
Appearance | White Powder |
Purity | 99% |
Melting Point | 179-181 °C |
Boiling Point | 606.9±55.0 °C |
Density | 1.390±0.06 g/cm3 |
Storage | 2-8°C(protect from light) |
Application | Pharmaceutical raw materials; The raw material; Intermediates |
Usage | Bifendate is commonly used in the pharmaceutical industry. |
Application
This product has a certain effect on the improvement of the main symptoms of hepatitis such as liver pain, weakness, abdominal distension, but it has no effect on the change of hepatosplenomegaly. It is suitable for patients with prolonged hepatitis and long-term single aminotransferase abnormality.
Specifications
Test Items |
Specification |
Description |
White to off white crystalline powder |
Melting point |
180-183°C |
Identification |
Positive reaction in accrod CP standard |
Related substances |
In accord CP |
Loss on drying |
≤0.5% |
Residue on ignition |
≤0.1% |
Chloride |
≤0.014% |
Heavy Metals |
≤20ppm |
Clarity of solution |
Conform to standard |
Assay(Calculation dry product) |
97.0%-103.0% |
Yanxi (shandong) New Material Co.,LTD is a professional research and development of the production of lead diacetate trihydrate, 2-
phenylethylamide enterprises. The key members of the company are established by local well-known entrepreneurs and professional engineers
under the call and support of the party's "low-carbon environmental protection, safety and stability". under the innovation in traditional
production equipment and technology, the use of "high temperature cooling" and "plastic basin crystallization" technology, on the basis of
reducing the cost of products to make the quality of products to the same industry. With the efforts of all the staff of the company, we have
established many cooperative companies in Shan Dong, He Nan, Guang Dong and other places in recent decades.
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Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,
we will send you free goods for replacement or refund your loss.
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